AFAP (attenuated familial adenomatous polyposis) is a condition caused by a genetic mutation which causes the growth of colorectal polyps that have the potential to become cancerous. Since the risk of developing colon cancer is higher for two out of... (Continue reading)
Alcohol-induced flushing is caused by an inherited deficiency in an enzyme called aldehyde dehydrogenase 2 (ALDH2) and recent studies show that people with this deficiency are more exposed to the risk of developing esophageal cancer (specifically squamous cell carcinoma) from... (Continue reading)
Myeloproliferative disorders (MPDs) are a group of blood cancers characterized by the excess production of red and white blood cells, many cases of which being caused by a mutation in a gene called JAK2. A recent study carried out at... (Continue reading)
A new drug could prove to be more effective in cancer treatment as tests show that it is about 200 times more active in killing tumor cells. The active agent comes from a class of drugs called bisphosphonates and it... (Continue reading)
Src is an enzyme from the family of protein tyrosine kinases and it was the first cancer-causing gene discovered at the beginning of the 20th century. It has control over cell metabolism, division and death and while its function is... (Continue reading)
The DNA inside cells is under continuous attack from heat, radiation and oxygen and one response of the cell to this outside factors is oxidative stress, which represents an imbalance in cell metabolism and it is related to a sum... (Continue reading)
Genetic instability is common for all the cells in the human body and it consists, among others, in double-strand breaks in the DNA cells. This occurs when both strands in the double helix are severed and while usually cells have... (Continue reading)