Too Good To Be True? Than For Sure It Isn`t! Overdosing and Insufficiency of Vitamin A Produces Negative Effects on Our Body
Overdosing vitamin A may seem rather harmless to most people, but recent studies presented in the FASEB Journal present the situation as the other way round. It is well known that vitamin A represents a key in the cellular production of energy. Even though this type of vitamin is recommended for the human body, it should be known that there is a correct dose in which it can be taken. If one does not have the necessary amount of vitamin A in his organism or takes too much, negative effects will shortly appear. The amalgam of drinks, drugs and foods comprising this vitamin may prove to be an overdose for that person who consumes them.
The team of scientists conducting this research came from from the Sloan-Kettering Institute for Cancer Research in New York. One of the authors of this research concerning the effects of vitamin A over the human body, Ulrich Hammerling stated that his team of researchers focused both on the positive effects this supplement has over the human body as well as on the negative side-effects an overdose with this type of vitamin may inflict on a person. Even though there are few cases in our nowadays community of insufficiency of vitamin A, people tend to think that large amounts of this vitamin represent no harm. However, overdosing on vitamin A may lead to deregulations in the cellular energy production process with negative outcomes such as uncontrollable cellular growth or a high cell mortality rate.
As stated previously in the article, vitamin A represents an important nutritional agent for the human body and even more for the fetal growth. However, until these days the negative effects of overdosing from vitamin A remained vaguely known and even unnoticed. This recent research presented the potentially negative effects of this type of overdose or insufficiency such as organ damages, for example.
The research conducted by the team from the Sloan-Kettering Institute for Cancer Research showed the causes for the appearance of these negative effects and also, the positive role vitamin A plays in counteracting cancer. For their study, the scientists underwent research on various cellular cultures coming from mice and human beings. The team of researchers strived to observe the genetic transformations involved in the energy production process at the mitochondrial level. The cellular samples were bred on the one hand with vitamin A embedded in them and on the other hand without its presence. The researchers studied the effects and modifications that took place at several levels of the energy production process. Outcomes proved that retinol which is an important element of vitamin A is also a key agent in the metabolic process of mitochondria and also plays the role of some kind of a food sensor in the process of cellular energy production. If there is either an insufficiency or an overdose of vitamin A in the organism, the mitochondria does not metabolize as it should properly do causing damage to the body`s organs.
As the chief editor of the FASEB Journal Gerald Weissmann stated as a conclusion for the presented study, it seems that the negative effects of vitamin A go deep in the human body affecting the nuclei of the cells and at the same time the state of one`s health due to the organ damage it may cause. Those who make over-use of beauty products rich in vitamin A should be aware of the overdose negative effects which may lead in the long-run to deadly effects.
